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Home Products Medical Products High Purity Bioprocessing Film

High Purity Bioprocessing Film

NEXCEL® BIO1250 10-Layer Single-Use Bioprocessing Film

Engineered with ultra-pure contact layer to ensure maximum protein yield and high cell viability by reducing the risk of growth-inhibiting degradation byproducts like bDtBPP.

  • Performance Across the Bioprocess Lifecycle

Exceptional performance in critical applications: cell expansion, sterile storage, sampling, harvesting, and downstream purification.

  • Advanced 10-Layer Structural Integrity

Our durable 10-layer architecture places critical barrier layers within a neutral plane, resisting stress whitening and abrasions during frozen transport and intensive handling.

  • Rigorous Quality & Regulatory Standards

Manufactured to ensure non-negotiable safety and consistency for high-stakes pharmaceutical and biotech manufacturing.

Overview

NEXCEL® BIO1250 is a premier, 10-layer single-use bioprocessing film meticulously engineered for high-consequence biotech manufacturing and Cell & Gene Therapy (CGT) applications. 

Designed to meet the exacting purity demands of system integrators and pharmaceutical suppliers, BIO1250 provides a neutral, ultra-pure environment that preserves the integrity of sensitive cell structures.

By prioritizing chemical inertness and structural resilience, this film ensures consistent performance across the entire bioprocess lifecycle—from upstream cell expansion to downstream purification and final frozen transport.

The NEXCEL® brand BIO1250 bioprocessing film is meticulously engineered to excel in critical bioprocessing applications, offering exceptional performance in cell expansion, storage, sampling, harvesting, and purification.

Nexcel_TenLayerFilmArchitecture_v2

Features and Benefits

  • Cell-Friendly Contact Layer: Engineered to eliminate the formation of bDtBPP—a known growth-inhibiting byproduct—while maintaining an exceptionally low extractable and leachable (E&L) profile for maximum cell viability and protein yield.
  • Neutral Plane Architecture: A robust 10-layer design that protects critical barrier layers within a neutral plane, resisting stress whitening and abrasions even at temperatures reaching -80°C.
  • Redundant Gas Barriers: Features fortified oxygen and moisture transmission control to maintain media stability and product integrity over extended durations.
  • Universal Integration: Optimized for superior seal strength and a wide sealing window, ensuring full compatibility with various 2D/3D container designs and standard port/tubing configurations.
  • Mechanical Resilience: High resistance to scuffs and punctures, significantly reducing the risk of container failure and costly batch rejection.

Product Details

  • Scalable Volume: 150 mL to 5,000+ L Volume range from 150 mL to 5,000+ L
  • Advanced Architecture: Clear, coextruded 10-layer polyethylene-based film with integrated EVOH gas barrier.
  • Pure Chemistry: Animal-Derived Ingredient Free (ADIF) and engineered with raw materials containing no intentional PFAS or phosphite stabilizers.
  • Versatile Formats: Optimized for 2D and 3D bioprocessing bag configurations.
  • Ultra-Clean Winding: Available in single-wound or double-wound formats to ensure superior interior film cleanliness.
  • Certified Manufacturing: Produced in an ISO Class 7 cleanroom under ISO 15378 quality standards.

Downloads

Access comprehensive data sheets and technical specifications to support your material qualification process. Contact us to request a product Validation Guide.